The new version is designed to tackle "new" health concerns, like smallpox, polio, SARS and human cases of new strains of human influenza, as well as potential biological, nuclear and chemical terrorist attacks. The DHHS press release goes on to say:
The regulations provide an algorithm to determine whether other incidents, including those of unknown causes or sources, may constitute public-health events of international concern, and as such must be reported to the WHO.
There's an algorithm for that?
On a related note... ever heard of Aircraft Disinsection? My spell checker hasn't.